Design, Synthesis, and Biological Evaluation of Novel Potent and Selective αvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Novel Potent and Selective αvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

Published:2005-01-28 Issue:4 Volume:48 Page:926-934
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Marugán Juan José¹,Manthey Carl¹,Anaclerio Beth¹,Lafrance Lou¹,Lu Tianbao¹,Markotan Tom¹,Leonard Kristi A.¹,Crysler Carl¹,Eisennagel Stephen¹,Dasgupta Malini¹,Tomczuk Bruce¹

Affiliation:

1. Johnson and Johnson Pharmaceutical Research & Development, L.L.C., 665 Stockton Drive, Suite 104, Exton, Pennsylvannia 19341

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049725u

Reference39 articles.

1. Integrins: Versatility, modulation, and signaling in cell adhesion

2. Integrin Structure

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