Selective Inhibitors of Bacterial t-RNA-(N1G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain-Reference-Cited by-同舟云学术

Selective Inhibitors of Bacterial t-RNA-(N1G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain

Published:2013-09-17 Issue:18 Volume:56 Page:7278-7288
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hill Pamela J.¹,Abibi Ayome¹,Albert Robert¹,Andrews Beth¹,Gagnon Moriah M.¹,Gao Ning¹,Grebe Tyler¹,Hajec Laurel I.¹,Huang Jian¹,Livchak Stephania¹,Lahiri Sushmita D.¹,McKinney David C.¹,Thresher Jason¹,Wang Hongming¹,Olivier Nelson¹,Buurman Ed T.¹

Affiliation:

1. Departments of Chemistry, ‡Biosciences and §Discovery Sciences, Infection Innovative Medicines Unit, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400718n

Reference21 articles.

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2. A primordial tRNA modification required for the evolution of life?

3. The universal ancestor

4. Prevention of Translational Frameshifting by the Modified Nucleoside 1-Methylguanosine

5. Chromosomal location and cloning of the gene (trmD) responsible for the synthesis of tRNA (m1G) methyltransferase in Escherichia coli K-12

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