Routes for the Synthesis of (2S)-2-Methyltetrahydropyran-4-one from Simple Optically Pure Building Blocks-Reference-Cited by-同舟云学术

Routes for the Synthesis of (2S)-2-Methyltetrahydropyran-4-one from Simple Optically Pure Building Blocks

Published:2009-12-03 Issue:1 Volume:14 Page:58-71
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Anderson Kevin R.¹,Atkinson Stéphanie L. G.¹,Fujiwara Takahiro¹,Giles Melvyn E.¹,Matsumoto Takaji¹,Merifield Eric¹,Singleton John T.¹,Saito Takao¹,Sotoguchi Tsukasa¹,Tornos James A.¹,Way Edward L.¹

Affiliation:

1. AstraZeneca R&D Charnwood, Process Research and Development, Bakewell Road, Loughborough, Leicestershire LE11 5RH, United Kingdom, and Takasago International Corporation, Corporate Research and Development Division, 4-11, 1-Chome, Nishi-Yawata, Hiratsuka City, Kanagawa, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op900163a

Reference56 articles.

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2. Efficient Syntheses of AZD4407 via Thioether Formation by Nucleophilic Attack of Organometallic Species on Sulphur

3. 4-Methoxy-2-methyltetrahydropyrans: chiral leukotriene biosynthesis inhibitors, related to ICI D2138, which display enantioselectivity

4. Asymmetric Syntheses of (S)-2-Methyl-3,4,5,6-tetrahydro-2H-pyran-4- one and (2S,6S)-2,6-trans-Dimethyl-3,4,5,6-tetrahydro-2H-pyran-4-one Which Employ a Common Lactol Intermediate

5. Enzymes in organic synthesis. 25. Heterocyclic ketones as substrates of horse liver alcohol dehydrogenase. Highly stereoselective reductions of 2-substituted tetrahydropyran-4-ones

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