Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection-Reference-Cited by-同舟云学术

Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection

Published:2014-01-10 Issue:5 Volume:57 Page:2033-2046
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Link John O.¹,Taylor James G.¹,Xu Lianhong¹,Mitchell Michael¹,Guo Hongyan¹,Liu Hongtao¹,Kato Darryl¹,Kirschberg Thorsten¹,Sun Jianyu¹,Squires Neil¹,Parrish Jay¹,Keller Terry¹,Yang Zheng-Yu¹,Yang Chris¹,Matles Mike¹,Wang Yujin¹,Wang Kelly¹,Cheng Guofeng¹,Tian Yang¹,Mogalian Erik¹,Mondou Elsa¹,Cornpropst Melanie¹,Perry Jason¹,Desai Manoj C.¹

Affiliation:

1. Medicinal Chemistry, ‡Drug Metabolism, §Biology, ±Formulation and Process Development, ∥Clinical Research, and ⊥Structural Chemistry, Gilead Sciences, 333 Lakeside Drive, Foster City, California 94404, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401499g

Reference53 articles.

1. Evolving epidemiology of hepatitis C virus

2. Integrating Phylodynamics and Epidemiology to Estimate Transmission Diversity in Viral Epidemics

3. Sustained Virologic Response to Antiviral Therapy for Chronic Hepatitis C Virus Infection: A Cure and So Much More

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