Identifying the Structural Requirements for Chromosomal Aberration by Incorporating Molecular Flexibility and Metabolic Activation of Chemicals-Reference-Cited by-同舟云学术

Identifying the Structural Requirements for Chromosomal Aberration by Incorporating Molecular Flexibility and Metabolic Activation of Chemicals

Published:2007-12-01 Issue:12 Volume:20 Page:1927-1941
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Mekenyan Ovanes¹,Todorov Milen¹,Serafimova Rossitsa¹,Stoeva Stoyanka¹,Aptula Aynur¹,Finking Robert¹,Jacob Elard¹

Affiliation:

1. Laboratory of Mathematical Chemistry, Bourgas As. Zlatarov University, 8010 Bourgas, Bulgaria, Safety Environmental Assurance Centre (SEAC), Unilever Colworth, Colworth House, Sharnbrook, Bedford MK44 1LQ, U.K., and Department of Product Safety, Regulations, Toxicology and Ecology, BASF Aktiengesellschaft, D-67056 Ludwigshafen, Germany

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx700249q

Reference47 articles.

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2. An Overview of Structure-Activity Relationships as an Alternative To Testing in Animals for Carcinogenicity, Mutagenicity, Dermal and Eye Irritation, and Acute Oral Toxicity

3. The present status of QSAR in toxicology

4. Development of structure-activity relationship rules for predicting carcinogenic potential of chemicals

5. Use of computer-assisted prediction of toxic effects of chemical substances

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