Membrane Fluidity Modulates Thermal Stability and Ligand Binding of Cytochrome P4503A4 in Lipid Nanodiscs

Author:

McClary Wynton D.1,Sumida John P.1,Scian Michele1,Paço Lorela1,Atkins William M.1

Affiliation:

1. Department of Medicinal Chemistry, University of Washington, Box 357610, Seattle, Washington 98195-7610, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Reference51 articles.

1. Guengerich, F. P. (2005) inCytochrome P450: Structure, mechanism, and biochemistry(Ortiz de Montellano, P., Ed.)3rd ed., pp423–430,Kluwer Academic/Plenum Publishers,New York.

2. The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

3. Cytochromes P450 and metabolism of xenobiotics

4. Clinical importance of the cytochromes P450

5. CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism

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