In-Depth Dissection of the P133R Mutation in Steroid 5β-Reductase (AKR1D1): A Molecular Basis of Bile Acid Deficiency
Author:
Affiliation:
1. Center of Excellence in Environmental Toxicology and Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine University of Pennsylvania, Philadelphia, Philadelphia, United States
Funder
National Institute of Environmental Health Sciences
National Institute of Diabetes and Digestive and Kidney Diseases
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.5b00816
Reference35 articles.
1. The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2. Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
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5. 5β-Dihydroprogesterone and steroid 5β–reductase decrease in association with human parturition at term
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