Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH Range-Reference-Cited by-同舟云学术

Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH Range

Published:2023-07-17 Issue:15 Volume:62 Page:2289-2300
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Yoon Michael C.¹²^ORCID,Phan Von¹²,Podvin Sonia¹,Mosier Charles¹,O’Donoghue Anthony J.¹,Hook Vivian¹²³^ORCID

Affiliation:

1. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, La Jolla, San Diego, California 92093, United States

2. Biomedical Sciences Graduate Program, University of California, La Jolla, San Diego, California 92093, United States

3. Department of Neurosciences and Department of Pharmacology, School of Medicine, University of California, La Jolla, San Diego, California 92093, United States

Funder

National Institute of Neurological Disorders and Stroke

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00139

Reference61 articles.

1. Functions of Lysosomes

2. Lysosomal Physiology

3. The lysosome as a cellular centre for signalling, metabolism and quality control

4. Cysteine cathepsins: From structure, function and regulation to new frontiers

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