Hydrophilic Sequence-Defined Cross-Linkers for Antibody–Drug Conjugates
Author:
Affiliation:
1. Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, 113 Ho Plaza, Ithaca, New York 14850, United States
2. Catalent Biologics, 5703 Hollis Street, Emeryville, California 94608, United States
Funder
Division of Chemistry
Division of Graduate Education
Cornell University
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.9b00713
Reference35 articles.
1. Strategies and challenges for the next generation of antibody–drug conjugates
2. Drug–Membrane Permeability across Chemical Space
3. Parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics
4. Investigation into Temperature-Induced Aggregation of an Antibody Drug Conjugate
5. Impact of Payload Hydrophobicity on the Stability of Antibody–Drug Conjugates
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