Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo

Author:

Woods Ben1,Silva Rúben D. M.2,Schmidt Claudia3,Wragg Darren3,Cavaco Marco4ORCID,Neves Vera4ORCID,Ferreira Vera F. C.2,Gano Lurdes25,Morais Tânia S.6ORCID,Mendes Filipa25ORCID,Correia João D. G.25ORCID,Casini Angela3ORCID

Affiliation:

1. Institute of Structural and Molecular Biology and Department of Biological Sciences, School of Science, Birkbeck University of London, Malet Street, London WC1E 7HX, United Kingdom

2. Centro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa Estrada Nacional 10, 2695-066 Bobadela, LRS, Portugal

3. Department of Chemistry, Technical University of Munich, Lichtenbergstrasse 4, 85748 Garching bei München, Germany

4. Instituto de Medicina Molecular João Lobo Antunes (iMM-JLA), Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal

5. Departamento de Engenharia e Ciências Nucleares (DECN), Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 2695-066 Bobadela, LRS, Portugal

6. Centro de Química Estrutural and Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal

Funder

European Social Fund

Fundação para a Ciência e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

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