Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells-Reference-Cited by-同舟云学术

Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells

Published:2019-03-13 Issue:4 Volume:30 Page:1150-1161
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Zom Gijs G.¹,Willems Marian M. J. H. P.²,Meeuwenoord Nico J.²,Reintjens Niels R. M.²,Tondini Elena¹,Khan Selina¹,Overkleeft Herman S.²^ORCID,van der Marel Gijsbert A.²,Codee Jeroen D. C.²^ORCID,Ossendorp Ferry¹,Filippov Dmitri V.²^ORCID

Affiliation:

1. Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands

2. Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC Leiden, The Netherlands

Funder

KWF Kankerbestrijding

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.9b00087

Reference47 articles.

1. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

2. Toll-like receptor agonists: current status and future perspective on their utility as adjuvants in improving antic ancer vaccination strategies

3. TLR Agonists for Cancer Immunotherapy: Tipping the Balance between the Immune Stimulatory and Inhibitory Effects

4. Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand–Peptide Conjugates

5. Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule

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