Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors-Reference-Cited by-同舟云学术

Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors

Published:2000-08-01 Issue:17 Volume:43 Page:3226-3232
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Maignan Sébastien¹,Guilloteau Jean-Pierre¹,Pouzieux Stéphanie¹,Choi-Sledeski Yong Mi¹,Becker Michael R.¹,Klein Scott I.¹,Ewing William R.¹,Pauls Henry W.¹,Spada Alfred P.¹,Mikol Vincent¹

Affiliation:

1. Department of Structural Biology, Aventis Pharma, 13, Quai J. Guesde, F-94403 Vitry/Seine, France, and Department of Medicinal Chemistry, Aventis Pharma, 500 Arcola Road, Collegeville, Pennsylvania 19426

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000940u

Reference20 articles.

1. Role of Thrombin Compared With Factor Xa in the Procoagulant Activity of Whole Blood Clots

2. Thrombin and factor Xa inhibitors

3. Low-Molecular-Weight Heparins

4. Structure of Human Des(1-45) Factor Xa at 2·2 Å Resolution

5. X-ray Structure of Active Site-inhibited Clotting Factor Xa

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