Assessing the Potential of N-Butyl-l-deoxynojirimycin (l-NBDNJ) in Models of Cystic Fibrosis as a Promising Antibacterial Agent

Author:

Esposito Anna1ORCID,Rossi Alice2,Stabile Maria3,Pinto Gabriella4ORCID,De Fino Ida2,Melessike Medede2,Tamanini Anna5,Cabrini Giulio6,Lippi Giuseppe5,Aureli Massimo7,Loberto Nicoletta7,Renda Mario8,Galietta Luis J. V.89,Amoresano Angela410,Dechecchi Maria Cristina5,De Gregorio Eliana3,Bragonzi Alessandra2,Guaragna Annalisa4ORCID

Affiliation:

1. Department of Chemical, Materials and Production Engineering, University of Naples Federico II, Naples I-80125, Italy

2. Infections and Cystic Fibrosis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan I-20132, Italy

3. Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples I-80131, Italy

4. Department of Chemical Sciences, University of Naples Federico II, Naples I-80126, Italy

5. Section of Clinical Biochemistry, Department of Engineering for Innovation Medicine, University of Verona, Verona I-37134, Italy

6. Center on Innovative Therapies for Cystic Fibrosis, Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara I-40121, Italy

7. Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan I-20054, Italy

8. Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Naples I-80078, Italy

9. Department of Translational Medical Sciences (DISMET), University of Naples Federico II, Naples I-80131, Italy

10. Istituto Nazionale Biostrutture e Biosistemi, Consorzio Interuniversitario, Rome I-00136, Italy

Funder

Fondazione per la Ricerca sulla Fibrosi Cistica

European Cystic Fibrosis Society

Publisher

American Chemical Society (ACS)

Reference77 articles.

1. Cystic fibrosis

2. Cystic fibrosis

3. Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

4. Cystic Fibrosis Mutation Database 2018. http://www.Genet.Sickkids.on.ca/Home.Html. (accessed June 2018).

5. Cystic Fibrosis Modulator Therapies

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