Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton’s Tyrosine Kinase-Reference-Cited by-同舟云学术

Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton’s Tyrosine Kinase

Published:2023-02-10 Issue:3 Volume:6 Page:410-421
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Li Kaixuan,Wang Mingqian,Akoglu Melike,Pollard Alyssa C.,Klecker John B.,Alfonso Patricia¹,Corrionero Ana¹,Prendiville Niall¹,Qu Wenchao^ORCID,Parker Matthew F. L.,Turkman Nashaat,Cohen Jules A.,Tonge Peter J.^ORCID

Affiliation:

1. Enzymlogic S.L., QUBE Technology Park, C/Santiago Grisolía, 2, 28760 Madrid, Spain

Funder

National Institute of Biomedical Imaging and Bioengineering

Stony Brook University

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00215

Reference42 articles.

1. Role of Bruton’s tyrosine kinase in B cells and malignancies

2. Targeting Bruton's tyrosine kinase in B cell malignancies

3. Medicinal Chemistry Strategies for the Development of Bruton’s Tyrosine Kinase Inhibitors against Resistance

4. The development of Bruton's tyrosine kinase (BTK) inhibitors from 2012 to 2017: A mini-review

5. Bruton’s Tyrosine Kinase (BTK) Inhibitors and Autoimmune Diseases: Making Sense of BTK Inhibitor Specificity Profiles and Recent Clinical Trial Successes and Failures

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