Experimentally Validated QSAR Model for Surface pKa Prediction of Heterolipids Having Potential as Delivery Materials for Nucleic Acid Therapeutics-Reference-Cited by-同舟云学术

Experimentally Validated QSAR Model for Surface pKa Prediction of Heterolipids Having Potential as Delivery Materials for Nucleic Acid Therapeutics

Published:2020-11-30 Issue:49 Volume:5 Page:32023-32031
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Dhumal Dinesh M.¹,Patil Pankaj D.²,Kulkarni Raghavendra V.³,Akamanchi Krishnacharya G.¹⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India

2. Department of Chemistry, Syracuse University, Syracuse, New York 13244, United States

3. BLDEA’s SSM College of Pharmacy & Research Centre, Vijayapura 586103, India

4. Department of Allied Health Sciences, Shri B.M. Patil Medical College, Hospital and Research Centre, BLDE Deemed to be University, Vijayapura 586103, India

Funder

Indo-French Centre for the Promotion of Advanced Research

Department of Science and Technology, Ministry of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.0c04931

Reference28 articles.

1. Review and analysis of FDA approved drugs using lipid-based formulations

2. Next-Generation Lipids in RNA Interference Therapeutics

3. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility

4. Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**

5. Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

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