New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies

Author:

Eissa Ibrahim H.1ORCID,Yousef Reda G.1,Elkaeed Eslam B.2,Alsfouk Aisha A.3ORCID,Husein Dalal Z.4,Ibrahim Ibrahim M.5,Ismail Ahmed6,Elkady Hazem1,Metwaly Ahmed M.78ORCID

Affiliation:

1. Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt

2. Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia

3. Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

4. Chemistry Department, Faculty of Science, New Valley University, El-Kharja 72511, Egypt

5. Biophysics Department, Faculty of Science, Cairo University, Giza 12613, Egypt

6. Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt

7. Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt

8. Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria 21934, Egypt

Funder

Princess Nourah Bint Abdulrahman University

AlMaarefa University

Publisher

American Chemical Society (ACS)

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