Virtual Screening and Biological Evaluation of Potential PD-1/PD-L1 Immune Checkpoint Inhibitors as Anti-Hepatocellular Carcinoma Agents-Reference-Cited by-同舟云学术

Virtual Screening and Biological Evaluation of Potential PD-1/PD-L1 Immune Checkpoint Inhibitors as Anti-Hepatocellular Carcinoma Agents

Published:2023-09-03 Issue:37 Volume:8 Page:33242-33254
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Kamal Monica A.¹^ORCID,Badary Hedy A.²^ORCID,Omran Dalia²,Shousha Hend I.²,Abdelaziz Ashraf O.²,El Tayebi Hend M.¹,Mandour Yasmine M.³⁴^ORCID

Affiliation:

1. Molecular Pharmacology Research Group, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Biotechnology, German University in Cairo, 11835 Cairo, Egypt

2. Endemic Medicine and Hepato-gastroenterology Department, Faculty of Medicine, Cairo University, 11562 Cairo, Egypt

3. School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, New Administrative Capital, 11578 Cairo, Egypt

4. Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, 11835 Cairo, Egypt

Funder

Egyptian Academy of Scientific Research and Technology

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c00279

Reference46 articles.

1. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

2. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

3. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors

4. Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1

5. Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2

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