Identification of Small-Molecule Regulators of Testicular Receptor 4 via a Drug Repurposing Screening
Author:
Affiliation:
1. Department of Urology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
Funder
National Natural Science Foundation of China
Zhejiang Medical and Health Plan Project
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acsomega.0c04623
Reference47 articles.
1. Recent advances in the study of testicular nuclear receptor 4
2. TR4 nuclear receptor promotes prostate cancer metastasisviaupregulation of CCL2/CCR2 signaling
3. TR4 nuclear receptor increases prostate cancer invasion via decreasing the miR-373-3p expression to alter TGFβR2/p-Smad3 signals
4. TR4 Nuclear Receptor Alters the Prostate Cancer CD133+ Stem/Progenitor Cell Invasion via Modulating the EZH2-Related Metastasis Gene Expression
5. Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating macrophages with alteration of the TIMP-1/MMP2/MMP9 signals
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