LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Cerebral Organoids

Author:

N. Costa Marcelo12ORCID,Goto-Silva Livia1ORCID,M. Nascimento Juliana13ORCID,Domith Ivan14ORCID,Karmirian Karina1ORCID,Feilding Amanda5ORCID,Trindade Pablo6ORCID,Martins-de-Souza Daniel178ORCID,K. Rehen Stevens12ORCID

Affiliation:

1. D’Or Institute for Research and Education, Rua Diniz Cordeiro, 30−Botafogo, Rio de Janeiro 22281-100, RJ, Brazil

2. Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro, Avenida Carlos Chagas Filho, 373 - Cidade Universitária, Rio de Janeiro 21941-902, RJ, Brazil

3. Department of Biochemistry and Tissue Biology, Institute of Biology, State University of Campinas, Rua Monteiro Lobato, 255 - Cidade Universitária Zeferino Vaz, Campinas 13083-862, SP, Brazil

4. Pioneer Science Initiative, D’Or Institute for Research and Education, Rua Diniz Cordeiro, 30−Botafogo, Rio de Janeiro22281-100, RJ, Brazil

5. Beckley Foundation, Beckley Park, Oxford OX3 9SY, United Kingdom

6. Department of Clinical and Toxicological Analysis (DACT), College of Pharmacy, Federal University of Rio de Janeiro, Avenida Carlos Chagas Filho, 373 - Cidade Universitária, Rio de Janeiro 21941-853, RJ, Brazil

7. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, State University of Campinas, Rua Monteiro Lobato, 255 - Cidade Universitária Zeferino Vaz, Campinas 13083-862, SP, Brazil

8. Experimental Medicine Research Cluster (EMRC), State University of Campinas, Rua Monteiro Lobato, 255 - Cidade Universitária Zeferino Vaz, Campinas 13083-862, SP, Brazil

Funder

Instituto D'Or de Pesquisa e Ensino

Beckley Foundation

Instituto Serrapilheira

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

Publisher

American Chemical Society (ACS)

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