Cell-Selective Pore Forming Antimicrobial Peptides of the Prodomain of Human Furin: A Conserved Aromatic/Cationic Sequence Mapping, Membrane Disruption, and Atomic-Resolution Structure and Dynamics

Author:

Sinha Sheetal12,Harioudh Munesh Kumar3,Dewangan Rikeshwer P.3,Ng Wun Jern,Ghosh Jimut Kanti3,Bhattacharjya Surajit1ORCID

Affiliation:

1. School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551

2. Advanced Environmental Biotechnology Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, 1 Cleantech Loop, Singapore 637141

3. Molecular and Structural Biology Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226 031, India

Funder

Ministry of Education - Singapore

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference80 articles.

1. O’Neill, J. Tackling Drug-Resistant Infections Globally: Final Report and Recommendations. Review on Antimicrobial Resistance, 2016.

2. Antibiotic resistance sweeping developing world

3. Control, C. F. D. Prevention, Antibiotic resistance threats in the United States, 2013. Centres for Disease Control and Prevention

4. US Department of Health and Human Services, 2013.

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