Synthesis and Biological Activity of 2-Chloro-8-methoxy-5-methyl-5<i>H</i>-indolo [2,3-<i>b</i>] Quinoline for the Treatment of Colorectal Cancer by Modulating PI3K/AKT/mTOR Pathways-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of 2-Chloro-8-methoxy-5-methyl-5H-indolo [2,3-b] Quinoline for the Treatment of Colorectal Cancer by Modulating PI3K/AKT/mTOR Pathways

Published:2024-07-02 Issue:28 Volume:9 Page:30698-30707
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Ma Yunhao¹,Zhu Hongmei¹,Jiang Xinrong¹,Zhou Zhongkun¹,Zhou Yong¹,Tian Yanan²,Tu Lixue¹,Lu Juan¹^ORCID,Niu Yuqing¹,Du Liqian¹,Si Zhenzhen¹,Fang Hong¹,Liu Huanxiang²^ORCID,Liu Yingqian¹^ORCID,Chen Peng¹

Affiliation:

1. School of Pharmacy, Lanzhou University, No. 199 Donggang West Road, Lanzhou, Gansu 730000, China

2. Faculty of Applied Sciences, Macao Polytechnic University, R. de Luís Gonzaga Gomes, Macao, Macau 999078, China

Funder

Lanzhou University

Technological Innovation Guidance Program of Gansu Province

Lanzhou City

Scientific Research Project of Gansu Medical Products Administration

Gansu Intellectual Property Project

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.4c03101

Reference35 articles.

1. Therapeutic Potential of Targeting PI3K/AKT Pathway in Treatment of Colorectal Cancer: Rational and Progress

2. Insulin-Like Growth Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer

3. Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020

4. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

5. Synthesis and biological activity of 1H-imidazo[4,5-f][1,10]phenanthroline as a potential antitumor agent with PI3K/AKT/mTOR signaling