A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity-Reference-Cited by-同舟云学术

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A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity

Published:2011-04-01 Issue:16 Volume:50 Page:3357-3368
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Blackler Ryan J.¹,Müller-Loennies Sven²,Brooks Cory L.¹,Evans Dylan W.¹,Brade Lore²,Kosma Paul³,Brade Helmut²,Evans Stephen V.¹

Affiliation:

1. Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8P 3P6, Canada

2. Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Parkallee 22, D-23845 Borstel, Germany

3. Department of Chemistry, University of Natural Resources and Life Sciences, A-1190 Vienna, Austria

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi101886v

Reference51 articles.

1. Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

2. T Cell-Dependent B Cell Activation

3. Intraclonal generation of antibody mutants in germinal centres

4. Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences

5. Mechanism and control of class-switch recombination

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1. Antigen binding by conformational selection in near-germline antibodies;Journal of Biological Chemistry;2022-05

2. Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude;Biochemistry;2018-12-20

3. Structural basis for germline antibody recognition of HIV-1 immunogens;eLife;2016-03-21

4. Structural Basis for Antibody Recognition of Lipid A;Journal of Biological Chemistry;2015-08

5. Antibody recognition of carbohydrate epitopes;Glycobiology;2015-06-01

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