Optimizing Natural Products by Biosynthetic Engineering: Discovery of Nonquinone Hsp90 Inhibitors-Reference-Cited by-同舟云学术

Optimizing Natural Products by Biosynthetic Engineering: Discovery of Nonquinone Hsp90 Inhibitors

Published:2008-08-23 Issue:18 Volume:51 Page:5494-5497
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Ming-Qiang¹,Gaisser Sabine¹,Nur-E-Alam Mohammad¹,Sheehan Lesley S.¹,Vousden William A.¹,Gaitatzis Nikolaos¹,Peck Gerrard¹,Coates Nigel J.¹,Moss Steven J.¹,Radzom Markus¹,Foster Teresa A.¹,Sheridan Rose M.¹,Gregory Matthew A.¹,Roe S. Mark¹,Prodromou Chrisostomos¹,Pearl Laurence¹,Boyd Susan M.¹,Wilkinson Barrie¹,Martin Christine J.¹

Affiliation:

1. Biotica Technology Limited, Chesterford Research Park, Nr. Saffron Walden, Essex CB10 1XL, United Kingdom, Section of Structural Biology, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, United Kingdom, CompChem Solutions, St. John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8006068

Reference26 articles.

1. Structure and Mechanism of the Hsp90 Molecular Chaperone Machinery

2. The Hallmarks of Cancer

3. HSP90 as a new therapeutic target for cancer therapy: the story unfolds

4. Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

Cited by 76 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Insights into the genomic and functional divergence of NAT gene family to serve microbial secondary metabolism;Scientific Reports;2024-06-28

2. The contemporary nexus of medicines security and bioprospecting: a future perspective for prioritizing the patient;Natural Products and Bioprospecting;2024-01-25

3. iPRESTO: Automated discovery of biosynthetic sub-clusters linked to specific natural product substructures;PLOS Computational Biology;2023-02-09

4. Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines;Biochemical Pharmacology;2023-01

5. iPRESTO: automated discovery of biosynthetic sub-clusters linked to specific natural product substructures;2022-08-06