High Accuracy Prediction of PROTAC Complex Structures

Author:

Ignatov Mikhail12,Jindal Akhil12,Kotelnikov Sergei12,Beglov Dmitri34,Posternak Ganna56,Tang Xiaojing5,Maisonneuve Pierre5ORCID,Poda Gennady78,Batey Robert A.6ORCID,Sicheri Frank5910ORCID,Whitty Adrian11ORCID,Tonge Peter J.12ORCID,Vajda Sandor311ORCID,Kozakov Dima12ORCID

Affiliation:

1. Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York 11794, United States

2. Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794, United States

3. Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, United States

4. Acpharis Inc., Holliston, Massachusetts 01746, United States

5. Center for Molecular, Cell and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario L4K-M9W, Canada

6. Department of Chemistry, University of Toronto, Toronto, Ontario L4K-M9W, Canada

7. Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, Ontario L4K-M9W, Canada

8. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario L4K-M9W, Canada

9. Department of Molecular Genetics, University of Toronto, Toronto, Ontario L4K-M9W, Canada

10. Department of Biochemistry, University of Toronto, Toronto, Ontario L4K-M9W, Canada

11. Department of Chemistry, Boston University, Boston, Massachusetts 02215, United States

12. Department of Chemistry, Stony Brook University, Stony Brook, New York 11794, United States

Funder

Division of Mathematical Sciences

Division of Computing and Communication Foundations

Office of the Director

National Institute of General Medical Sciences

Government of Ontario

Ontario Institute for Cancer Research

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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