Intramolecular C–C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis
Author:
Affiliation:
1. Skaggs Graduate School of Chemical and Biological Sciences, Scripps Research, Jupiter, Florida 33458, United States
2. Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Lemont, Illinois 60439, United States
Funder
NIH Office of the Director
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.2c08957
Reference47 articles.
1. Biosynthesis of Enediyne Natural Products
2. C-1027 Enediyne Chromophore: Presence of Another Active Form and Its Chemical Structure.
3. Distribution of neocarzinostatin conjugated to biotinylated chimeric monoclonal antibody Fab fragments after adminstration of avidin
4. Kedarcidin Chromophore: Synthesis of Its Proposed Structure and Evidence for a Stereochemical Revision
5. Total Synthesis and Structure Revision of the (−)-Maduropeptin Chromophore
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3. Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate;Nature Chemical Biology;2024-06-03
4. DNA Interaction and Cleavage Modes of Anthraquinone-Fused Enediynes: A Study on Tiancimycins, Yangpumicins, and Their Semisynthetic Analogues;Journal of Medicinal Chemistry;2024-03-14
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