Tracing of Acyl Carrier Protein-channeled Mitomycin Intermediates in <i>Streptomyces caespitosus</i> Facilitates Characterization of the Biosynthetic Steps for AHBA–GlcN Formation and Processing-Reference-Cited by-同舟云学术

Tracing of Acyl Carrier Protein-channeled Mitomycin Intermediates in Streptomyces caespitosus Facilitates Characterization of the Biosynthetic Steps for AHBA–GlcN Formation and Processing

Published:2022-08-09 Issue:32 Volume:144 Page:14945-14956
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Wang Sili¹,Cheng Yiyuan¹,Wang Xiaofeng²,Yang Qian¹,Liu Wen¹^ORCID

Affiliation:

1. State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

2. School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, 1 Sub-lane Xiangshan, Hangzhou 310024, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c06969

Reference45 articles.

1. Mitomycinoid Alkaloids: Mechanism of Action, Biosynthesis, Total Syntheses, and Synthetic Approaches

2. Mechanism of monofunctional and bifunctional alkylation of DNA by mitomycin C