Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death-Reference-Cited by-同舟云学术

Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death

Published:2022-08-03 Issue:32 Volume:144 Page:14706-14721
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Farmer Luke A.¹,Wu Zijun¹^ORCID,Poon Jia-Fei¹^ORCID,Zilka Omkar¹^ORCID,Lorenz Svenja M.²,Huehn Stephanie²,Proneth Bettina²,Conrad Marcus²,Pratt Derek A.¹^ORCID

Affiliation:

1. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada

2. Institute of Metabolism and Cell Death, Helmholtz Munich, Neuherberg 85764, Germany

Funder

Bundesministerium f?r Bildung und Forschung

Canada Foundation for Innovation

Deutsche Forschungsgemeinschaft

Natural Sciences and Engineering Research Council of Canada

H2020 European Research Council

Ontario Graduate Scholarship program

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c05252

Reference69 articles.

1. Ferroptosis: mechanisms, biology and role in disease

2. The Chemistry and Biology of Ferroptosis

3. The chemical basis of ferroptosis

4. Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture

5. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

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