Chemoenzymatic Synthesis of Glycosylated Glucagon-like Peptide 1: Effect of Glycosylation on Proteolytic Resistance and in Vivo Blood Glucose-Lowering Activity-Reference-Cited by-同舟云学术

Chemoenzymatic Synthesis of Glycosylated Glucagon-like Peptide 1: Effect of Glycosylation on Proteolytic Resistance and in Vivo Blood Glucose-Lowering Activity

Published:2009-04-10 Issue:17 Volume:131 Page:6237-6245
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Ueda Taichi¹,Tomita Kazuyoshi¹,Notsu Yoshihide¹,Ito Takaomi¹,Fumoto Masataka¹,Takakura Tomoaki¹,Nagatome Hirofumi¹,Takimoto Akio¹,Mihara Shin-Ichi¹,Togame Hiroko¹,Kawamoto Keiko¹,Iwasaki Takanori¹,Asakura Kenji¹,Oshima Takeo¹,Hanasaki Kohji¹,Nishimura Shin-Ichiro¹,Kondo Hirosato¹

Affiliation:

1. Discovery Research Laboratories, Settsu Plant, and Pharmaceutical Research Division, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan, and Graduate School of Advanced Life Science, Hokkaido University, Kita-ku, Sapporo 001-0021, Japan

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja900261g

Reference61 articles.

1. The Incretin Approach for Diabetes Treatment

2. Glucagon-like peptide 1(GLP-1) in biology and pathology

3. Glucagon-like peptide 1 and its derivatives in the treatment of diabetes

4. GLP-1 based therapy for type 2 diabetes

5. Glucagon-like peptide-1, glucose homeostasis and diabetes

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