Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain-Reference-Cited by-同舟云学术

Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain

Published:2015-02-09 Issue:4 Volume:6 Page:419-424
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Andrews Mark D.,af Forselles Kerry,Beaumont Kevin¹,Galan Sébastien R. G.,Glossop Paul A.,Grenie Mathilde,Jessiman Alan,Kenyon Amy S.,Lunn Graham,Maw Graham,Owen Robert M.²,Pryde David C.²,Roberts Dannielle,Tran Thien Duc

Affiliation:

1. Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, 610 Main Street, Cambridge, Massachusetts 02139, United States

2. Worldwide Medicinal Chemistry, Pfizer Neusentis, Granta Park, Cambridge CB21 6GS, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml500479v

Reference41 articles.

1. AN INTRODUCTION TO TRP CHANNELS

2. Transient receptor potential channels as therapeutic targets

3. Ion Channels as Therapeutic Targets: A Drug Discovery Perspective

4. Transient receptor potential (TRP) channels: a clinical perspective

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