Correlation and Prediction of Drug Molecule Solubility in Mixed Solvent Systems with the Nonrandom Two-Liquid Segment Activity Coefficient (NRTL−SAC) Model
Author:
Affiliation:
1. Aspen Technology, Inc., Ten Canal Park, Cambridge, Massachusetts 02141
2. AstraZeneca Pharmaceuticals Ltd., Process R&D, Macclesfield, Cheshire, SK10 2NA, United Kingdom
Publisher
American Chemical Society (ACS)
Subject
Industrial and Manufacturing Engineering,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ie051326p
Reference22 articles.
1. Solubility Modeling with a Nonrandom Two-Liquid Segment Activity Coefficient Model
2. A segment-based local composition model for the gibbs energy of polymer solutions
3. Effects of Solvent Medium on Solubility. V: Enthalpic and Entropic Contributions to the Free Energy Changes of Di-substituted Benzene Derivatives in Ethanol:Water and Ethanol:Cyclohexane Mixtures
4. Solubility of Paracetamol in Pure Solvents
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