Water Channel in the Binding Site of a High Affinity Anti-Methotrexate Antibody-Reference-Cited by-同舟云学术

Water Channel in the Binding Site of a High Affinity Anti-Methotrexate Antibody

Published:2014-06-05 Issue:23 Volume:53 Page:3719-3726
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Gayda Susan¹,Longenecker Kenton L.¹,Manoj Sharmila¹,Judge Russell A.¹,Saldana Sylvia C.¹,Ruan Qiaoqiao¹,Swift Kerry M.¹,Tetin Sergey Y.¹

Affiliation:

1. Diagnostics Research, Abbott Diagnostics Division and ‡Structural Biology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, United States

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi5001382

Reference33 articles.

1. Anatomy of the antibody molecule

2. Structural aspects of conformational changes in ligand binding by antibody fragments

3. An autoantibody to single-stranded DNA: Comparison of the three-dimensional structures of the unliganded fab and a deoxynucleotide-fab complex

4. Local and Transmitted Conformational Changes on Complexation of an Anti-sweetener Fab

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