Synthesis of Novel 2-Alkoxy-3-amino-3-arylpropan-1-ols and 5-Alkoxy-4-aryl-1,3-oxazinanes with Antimalarial Activity-Reference-Cited by-同舟云学术

Synthesis of Novel 2-Alkoxy-3-amino-3-arylpropan-1-ols and 5-Alkoxy-4-aryl-1,3-oxazinanes with Antimalarial Activity

Published:2009-05-22 Issue:13 Volume:52 Page:4058-4062
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

D’hooghe Matthias¹,Dekeukeleire Stijn¹,Mollet Karen¹,Lategan Carmen¹,Smith Peter J.¹,Chibale Kelly¹,De Kimpe Norbert¹

Affiliation:

1. Department of Organic Chemistry, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium, Division of Pharmacology, University of Cape Town, K45, OMB, Groote Schuur Hospital, Observatory, 7925, South Africa, Department of Chemistry and Institute of Infectious Disease & Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9002632

Reference55 articles.

1. Malaria: Burden of Disease

2. Perspective in Antimalarial Chemotherapy

3. Present Trends and Future Strategy in Chemotherapy of Malaria

4. Why Artemisinin and Certain Synthetic Peroxides are Potent Antimalarials. Implications for the Mode of Action

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