Controlled Modular Multivalent Presentation of the CD40 Ligand on P22 Virus-like Particles Leads to Tunable Amplification of CD40 Signaling

Author:

Goodall Cheri Peyton1ORCID,Schwarz Benjamin2,Selivanovitch Ekaterina1,Avera John3,Wang Joseph4ORCID,Miettinen Heini5ORCID,Douglas Trevor1ORCID

Affiliation:

1. Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, United States

2. Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, 903 South 4th Street, Hamilton, Montana 59840, United States

3. Walden Biosciences, One Kendall Square, Suite 7102, Cambridge, Massachusetts 02139, United States

4. Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, 700 HMC Crescent Road, Hershey, Pennsylvania 17033, United States

5. Department of Microbiology and Immunology, Montana State University, P.O. Box 173520, Bozeman, Montana 59717, United States

Funder

Indiana University

Human Frontier Science Program

National Science Foundation

Graduate Training Program in Qualitative and Chemical Biology

Publisher

American Chemical Society (ACS)

Subject

Biochemistry (medical),Biomedical Engineering,General Chemistry,Biomaterials

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