Differences in Enantioselective Hydroxylation of 2,2′,3,6-Tetrachlorobiphenyl (CB45) and 2,2′,3,4′,6-Pentachlorobiphenyl (CB91) by Human and Rat CYP2B Subfamilies

Author:

Inui Hideyuki12ORCID,Ito Terushi2,Miwa Chiharu3,Haga Yuki4,Kubo Makoto5,Itoh Toshimasa5ORCID,Yamamoto Keiko5ORCID,Miyaoka Masayuki6,Mori Tadashi6ORCID,Tsuzuki Harunobu2,Mise Shintaro2,Goto Erika2,Matsumura Chisato4,Nakano Takeshi7ORCID

Affiliation:

1. Biosignal Research Center, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe, Hyogo 657-8501, Japan

2. Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe, Hyogo 657-8501, Japan

3. Faculty of Agriculture, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe, Hyogo 657-8501, Japan

4. Hyogo Prefectural Institute of Environmental Sciences, 3-1-18 Yukihiracho, Suma-ku, Kobe, Hyogo 654-0037, Japan

5. Laboratory of Drug Design and Medicinal Chemistry, Showa Pharmaceutical University, 3-3165 Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan

6. Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan

7. Research Center for Environmental Preservation, Osaka University, 2-4 Yamadaoka, Suita, Osaka 565-0871, Japan

Funder

Core Research for Evolutional Science and Technology

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

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