Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles-Reference-Cited by-同舟云学术

Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles

Published:2010-03-19 Issue:8 Volume:53 Page:3075-3085
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Velázquez Francisco¹,Sannigrahi Mousumi¹,Bennett Frank¹,Lovey Raymond G.¹,Arasappan Ashok¹,Bogen Stéphane¹,Nair Latha¹,Venkatraman Srikanth¹,Blackman Melissa¹,Hendrata Siska¹,Huang Yuhua¹,Huelgas Regina¹,Pinto Patrick¹,Cheng Kuo-Chi¹,Tong Xiao¹,McPhail Andrew T.¹,Njoroge F. George¹

Affiliation:

1. Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033-1300

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9016027

Reference26 articles.

1. aWorld Health Organization (WHO). Hepatitis C. Fact Sheet No. 164.http://www.who.int/mediacentre/factsheets/fs164/en/(revised October 2000) .

2. Epidemiology of Hepatitis C: Geographic Differences and Temporal Trends

3. Scope of worldwide hepatitis C problem