Property- and Structure-Guided Discovery of a Tetrahydroindazole Series of Interleukin-2 Inducible T-Cell Kinase Inhibitors-Reference-Cited by-同舟云学术

Property- and Structure-Guided Discovery of a Tetrahydroindazole Series of Interleukin-2 Inducible T-Cell Kinase Inhibitors

Published:2014-06-27 Issue:13 Volume:57 Page:5714-5727
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Burch Jason D.¹,Lau Kevin¹,Barker John J.²,Brookfield Fred²,Chen Yong³,Chen Yuan¹,Eigenbrot Charles¹,Ellebrandt Claire⁴,Ismaili M. Hicham A.¹,Johnson Adam¹,Kordt Daniel⁴,MacKinnon Colin H.²,McEwan Paul A.²,Ortwine Daniel F.¹,Stein Daniel B.⁴,Wang Xiaolu⁴,Winkler Dirk⁴,Yuen Po-Wai³,Zhang Yamin³,Zarrin Ali A.¹,Pei Zhonghua¹

Affiliation:

1. Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States

2. Evotec (U.K.) Ltd., 114 Milton Park, Abingdon, Oxfordshire OX14 4SA, United Kingdom

3. Pharmaron Beijing Co. Ltd., No. 6 Tai He Road, BDA, 100176, Beijing, China

4. Manfred Eigen Campus, Evotec AG, Essener Bogen 7, D-22419, Hamburg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500550e

Reference49 articles.