Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids-Reference-Cited by-同舟云学术

Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids

Published:2005-12-27 Issue:2 Volume:49 Page:748-759
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Salem Ola I. A.¹,Frotscher Martin¹,Scherer Christiane¹,Neugebauer Alexander¹,Biemel Klaus¹,Streiber Martina¹,Maas Ruth¹,Hartmann Rolf W.¹

Affiliation:

1. 8.2 Pharmaceutical and Medicinal Chemistry, Saarland University, P.O. Box 15 11 50, D-66041 Saarbrücken, Germany, and Pharmacelsus CRO, Science Park 2, D-66123 Saarbrücken, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050728w

Reference63 articles.

1. Characterization of 5α-reductase gene expression in stroma and epithelium of human prostate

2. STEROID 5α-REDUCTASE: TWO GENES/TWO ENZYMES

3. Dihydrotestosterone and the concept of 5α-reductase inhibition in human benign prostatic hyperplasia

4. Pharmacological Options in the Treatment of Benign Prostatic Hyperplasia

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