Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M-Reference-Cited by-同舟云学术

Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M

Published:2006-02-01 Issue:4 Volume:49 Page:1379-1387
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kovalevsky Andrey Yu.¹,Tie Yunfeng¹,Liu Fengling¹,Boross Peter I.¹,Wang Yuan-Fang¹,Leshchenko Sofiya¹,Ghosh Arun K.¹,Harrison Robert W.¹,Weber Irene T.¹

Affiliation:

1. Department of Biology and Department of Chemistry, Molecular Basis of Disease, and Department of Computer Science, Georgia State University, Atlanta, Georgia 30303, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, and Department of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, Indiana 47907

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050943c

Reference41 articles.

1. New Approaches toward Anti-HIV Chemotherapy

2. INHIBITORS OF HIV-1 PROTEASE: A Major Success of Structure-Assisted Drug Design

3. Classifying toxicity and pathology by gene-expression profile – taking a lead from studies in neoplasia

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