Synthesis of Dibenzazepinones by Palladium-Catalyzed Intramolecular Arylation of o-(2′-Bromophenyl)anilide Enolates

Author:

Pan Xiaohong1,Wilcox Craig S.1

Affiliation:

1. Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference24 articles.

1. A multigram chemical synthesis of the γ-secretase inhibitor LY411575 and its diastereoisomers

2. aWu, J. T.; Tung, J. S.; Thorsett, E. D.; Pleiss, M. A.; Nissen, J. S.; Neitz, J.; Latimer, L. H.; John, V.; Freedman, S.; Britton, T. C.; Audia, J. E.; Reel, J. K.; Mabry, T. E.; Dressman, B. A.; Cwi, C. L.; Droste, J. J.; Henry, S. S.; McDaniel, S. L.; Scott, W. L.; Stucky, R. D.; Porter, W.PCT Int. Appl. WO 9828268 A 2:889, 1998.

3. bAudia, J. E.; Hyslop, P. A.; Nissen, J. S.; Thompson, R. C.; Tung, J. S.; Tanner, L. I.WO 00/19210, 2000.

4. Atropisomeric Properties of the Dibenzo[b,d]azepin-6-one Nucleus

5. Application of the Palladium-Catalyzed Borylation/Suzuki Coupling (BSC) Reaction to the Synthesis of Biologically Active Biaryl Lactams

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