Ortho-Deuteration of Aromatic Aldehydes via a Transient Directing Group-Enabled Pd-Catalyzed Hydrogen Isotope Exchange-Reference-Cited by-同舟云学术

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Ortho-Deuteration of Aromatic Aldehydes via a Transient Directing Group-Enabled Pd-Catalyzed Hydrogen Isotope Exchange

Published:2021-09-13 Issue:19 Volume:86 Page:13350-13359
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Kong Junhua¹²,Jiang Zhi-Jiang¹^ORCID,Xu Jiayuan³,Li Yan¹²,Cao Hong¹,Ding Yanan¹,Tang Bencan³^ORCID,Chen Jia¹,Gao Zhanghua¹^ORCID

Affiliation:

1. School of Biological and Chemical Engineering, NingboTech University, Ningbo 315100, P. R. China

2. College of Chemical and Biological Engineering, Zhejiang University, Zhejiang 310027, P. R. China

3. Department of Chemical and Environment Engineering, The University of Nottingham Ningbo China, Ningbo 315100, P. R. China

Funder

Natural Science Foundation of Ningbo

Ministry of Science and Technology of the People's Republic of China

Ningbo Municipal Bureau of Science and Technology

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c01411

Reference73 articles.

1. Large deuterium isotope effects and their use: a historical review

2. The Deuterium Isotope Effect

3. Applications of Deuterium in Medicinal Chemistry

4. Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

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1. Geometric constraints regulated regioselectivity: Pd-catalyzed α-deuteration of pyridines with secondary phosphine oxide;Chemical Communications;2024

2. Nickel-catalyzed regioselective hydrogen isotope exchange accelerated by 2-pyridones;Chemical Communications;2024

3. Pd-Catalyzed Regioselective Deuteration of Indole’s C4-Position with Transient Directing Groups;The Journal of Organic Chemistry;2023-11-22

4. B(C₆F₅)₃-Catalyzed Intramolecular Hydroalkoxylation Deuteration Reactions of Unactivated Alkynyl Alcohols;Organic Letters;2023-09-12

5. Electrochemical Synthesis of Phthalimidine‐d₂ with Heavy Water as Deuterium Source;Advanced Synthesis & Catalysis;2023-08-09

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