Stereoretentive Nucleophilic Substitution at the Tetrasubstituted Carbon of Galiellalactone
Author:
Affiliation:
1. Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Naturvetarvägen 14, 22100 Lund, Sweden
2. Glactone Pharma Development, Kullagatan 8, SE-25220 Helsingborg, Sweden
Funder
Faculty of Science, Lund University
Glactone Pharma AB
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c00152
Reference9 articles.
1. Inhibition of interleukin-6 signaling by galiellalactone
2. Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
3. Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer
4. Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3
5. Galiellalactone Is a Direct Inhibitor of the Transcription Factor STAT3 in Prostate Cancer Cells
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