Application of Transition-Metal Catalysis, Biocatalysis, and Flow Chemistry as State-of-the-Art Technologies in the Synthesis of LCZ696

Author:

Gu Xingxian1,Zhao Jibin1,Chen Like1,Li Yunzhong1,Yu Bo1,Tian Xiangguang1,Min Zhongcheng1,Xu Su1,Gu Huijuan1,Sun Junjie1,Lu Xiaoquan1,Chang Meng1,Wang Xufan1,Zhao Liqun1,Ye Shengqing1,Yang Hongwei1ORCID,Tian Yingtao1,Gao Feng1,Gai Yu1,Jia Guanghua2,Wu Jingjing2,Wang Yan2,Zhang Jianghua2,Zhang Xuesong2,Liu Weichun2,Gu Xin2,Luo Xi2,Dong Hai2,Wang Huaimin2,Schenkel Berthold3,Venturoni Francesco3,Filipponi Paolo3ORCID,Guelat Bertrand3ORCID,Allmendinger Thomas3,Wietfeld Bernhard3,Hoehn Pascale3,Kovacic Nikola3,Hermann Luca3,Schlama Thierry3,Ruch Thomas3,Derrien Nadine4,Piechon Philippe5,Kleinbeck Florian3ORCID

Affiliation:

1. Suzhou Novartis Technical Development Co., Ltd., #18-1 Tonglian Road, Bixi Subdistrict, Changshu City, Jiangsu Province 215537, P.R. China

2. Novartis Pharmaceuticals (China) Suzhou Operations, Riverside Industrial Park Changshu Economic Development Zone, #18 Tonglian Road, Changshu, Jiangsu Province 215537, P.R. China

3. Chemical & Analytical Development, Novartis Pharma AG, 4056 Basel, Switzerland

4. Pharmaceutical & Analytical Development, Novartis Pharma AG, 4056 Basel, Switzerland

5. Novartis Institutes for Biomedical Research, Novartis Pharma AG, 4056 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

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