Design, Synthesis, and Antifungal Activity of 16,17-Dihydroheronamide C and ent-Heronamide C-Reference-Cited by-同舟云学术

Design, Synthesis, and Antifungal Activity of 16,17-Dihydroheronamide C and ent-Heronamide C

Published:2021-11-16 Issue:23 Volume:86 Page:16249-16258
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Kanoh Naoki¹²^ORCID,Terashima Ryusei³,Nishiyama Hiromichi³,Terajima Yuta³,Nagasawa Shota³^ORCID,Sasano Yusuke³^ORCID,Iwabuchi Yoshiharu³,Saito Hiroaki⁴,Egoshi Syusuke⁵,Dodo Kosuke⁵^ORCID,Sodeoka Mikiko⁵^ORCID,Pan Chengqian⁶,Ikeuchi Yoshinobu⁶,Nishimura Shinichi⁷^ORCID,Kakeya Hideaki⁶^ORCID

Affiliation:

1. School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan

2. Institute of Medicinal Chemistry, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan

3. Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aza-aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan

4. Faculty of Pharmaceutical Sciences, Hokuriku University, 3 Kanagawamachi, Kanazawa, Ishikawa 920-1181, Japan

5. Synthetic Organic Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

6. Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Shimo-Adachi-cho, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan

7. Department of Biotechnology, Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo 113-8657, Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Tokyo Biochemical Research Foundation

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c01761

Reference23 articles.

1. Toward the Creation of Induced Pluripotent Small (iPS) Molecules: Establishment of a Modular Synthetic Strategy for the Heronamide C-type Polyene Macrolactams and Their Conformational and Reactivity Analysis

2. Chemical diversity and mode of action of natural products targeting lipids in the eukaryotic cell membrane

3. Natural polyenic macrolactams and polycyclic derivatives generated by transannular pericyclic reactions: optimized biogenesis challenging chemical synthesis

4. Natural products-prompted chemical biology: phenotypic screening and a new platform for target identification

5. Structure and Biological Activity of 8-Deoxyheronamide C from a Marine-Derived Streptomyces sp.: Heronamides Target Saturated Hydrocarbon Chains in Lipid Membranes

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