Engineered CRISPR Systems for Next Generation Gene Therapies
Author:
Affiliation:
1. School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona 85281, United States
2. Center for Regenerative Medicine, Mayo Clinic, Phoenix, Arizona 85054, United States
Funder
Defense Advanced Research Projects Agency
Publisher
American Chemical Society (ACS)
Subject
Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acssynbio.7b00011
Reference137 articles.
1. Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
2. Intervening Sequences of Regularly Spaced Prokaryotic Repeats Derive from Foreign Genetic Elements
3. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
4. The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
5. Molecular recordings by directed CRISPR spacer acquisition
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