Simulations Reveal High Efficiency and Confinement of a Population Suppression CRISPR Toxin-Antidote Gene Drive
Author:
Affiliation:
1. Center for Bioinformatics, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
Funder
Peking University
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acssynbio.2c00611
Reference67 articles.
1. How driving endonuclease genes can be used to combat pests and disease vectors
2. Engineering the Composition and Fate of Wild Populations with Gene Drive
3. Gene Drive: Evolved and Synthetic
4. Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex
5. Population management using gene drive: molecular design, models of spread dynamics and assessment of ecological risks
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1. Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila;Nature Communications;2024-09-14
2. Performance characteristics allow for confinement of a CRISPR toxin–antidote gene drive for population suppression in a reaction–diffusion model;Proceedings of the Royal Society B: Biological Sciences;2024-06
3. Making waves: Comparative analysis of gene drive spread characteristics in a continuous space model;Molecular Ecology;2023-09-11
4. Population suppression by release of insects carrying a dominant sterile homing gene drive targetingdoublesexinDrosophila;2023-07-17
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