Balancing the AspC and AspA Pathways of <i>Escherichia coli</i> by Systematic Metabolic Engineering Strategy for High-Efficient <scp>l</scp>-Homoserine Production-Reference-Cited by-同舟云学术

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Balancing the AspC and AspA Pathways of Escherichia coli by Systematic Metabolic Engineering Strategy for High-Efficient l-Homoserine Production

Published:2024-07-23 Issue:8 Volume:13 Page:2457-2469
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Chen Yuanyuan¹²,Huang Lianggang¹²,Yu Tao¹²,Yao Yuan¹²,Zhao Mingming¹²,Pang Aiping¹²,Zhou Junping¹²,Zhang Bo¹²,Liu Zhiqiang¹²^ORCID,Zheng Yuguo¹²^ORCID

Affiliation:

1. The National and Local Joint Engineering Research Center for Biomanufacturing of Choral Chemicals, Zhejiang University of Technology, Hangzhou 310014, PR China

2. Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, PR China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.4c00208

Reference59 articles.

1. Construction of a synthetic metabolic pathway for the production of 2,4-dihydroxybutyric acid from homoserine

2. Highly efficient biosynthesis of spermidine from L-homoserine and putrescine using an engineered Escherichia coli with NADPH self-sufficient system

3. Synthesis of chiral 1,4-oxazepane-5-carboxylic acids from polymer-supported homoserine

4. Metabolic Engineering of a Homoserine-Derived Non-Natural Pathway for the De Novo Production of 1,3-Propanediol from Glucose

5. Highly efficient production of L-homoserine in Escherichia coli by engineering a redox balance route

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