Ranking Ligand Affinity for the DNA Minor Groove by Experiment and Simulation-Reference-Cited by-同舟云学术

Ranking Ligand Affinity for the DNA Minor Groove by Experiment and Simulation

Published:2010-07-30 Issue:8 Volume:1 Page:376-380
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Wittayanarakul Kitiyaporn¹,Anthony Nahoum G.¹,Treesuwan Witcha²,Hannongbua Supa²,Alniss Hasan¹,Khalaf Abedawn I.³,Suckling Colin J.³,Parkinson John A³,Mackay Simon P.¹

Affiliation:

1. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, United Kingdom

2. Chemistry Department and Center of Nanotechnology, Kasetsart University, Bangkok 10900, Thailand

3. WestCHEM Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml100047n

Reference25 articles.

1. Recognition of the DNA minor groove by pyrrole-imidazole polyamides

2. The molecular origin of DNA-drug specificity in netropsin and distamycin.

3. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin.

4. Antibiotic-DNA interactions: intermolecular nuclear Overhauser effects in the netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) complex in solution.

5. Design of peptides that bind in the minor groove of DNA at 5'-(A,T)G(A,T)C(A,T)-3' sequences by a dimeric side-by-side motif

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