De Novo Design of Multitarget Ligands with an Iterative Fragment-Growing Strategy-Reference-Cited by-同舟云学术

De Novo Design of Multitarget Ligands with an Iterative Fragment-Growing Strategy

Published:2014-03-18 Issue:4 Volume:54 Page:1235-1241
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Shang Erchang¹,Yuan Yaxia²,Chen Xinyi¹,Liu Ying¹²,Pei Jianfeng²,Lai Luhua¹²³

Affiliation:

1. BNLMS, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

2. Center for Quantitative Biology, AAIS, Peking University, Beijing 100871, China

3. Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci500021v

Reference35 articles.

1. Rediscovering the sweet spot in drug discovery

2. Why is cancer drug discovery so difficult?

3. Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

4. How to design multi-target drugs

5. Multi-target therapeutics: when the whole is greater than the sum of the parts

Cited by 54 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent Advances in Automated Structure-Based De Novo Drug Design;Journal of Chemical Information and Modeling;2024-03-14

2. Multitargeting HDAC Inhibitors Containing a RAS/RAF Protein Interfering Unit;Journal of Medicinal Chemistry;2024-01-23

3. In silico Strategy: A Promising Implement in the Development of Multitarget Drugs against Neurodegenerative Diseases;Current Topics in Medicinal Chemistry;2023-11

4. Multi-targeted HDAC Inhibitors as Anticancer Agents: Current Status and Future Prospective;Current Medicinal Chemistry;2023-07

5. Discovery of dual S-RBD/NRP1-targeting peptides: structure-based virtual screening, synthesis, biological evaluation, and molecular dynamics simulation studies;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-05-17