HPLC/ICP-MS in Combination with “Reverse” Online Isotope Dilution in Drug Metabolism Studies
Author:
Affiliation:
1. Department of Analytical Chemistry, Ghent University, Krijgslaan 281-S12, 9000 Ghent, Belgium
2. Drug Safety Sciences, Janssen R&D, Turnhoutseweg 30, 2340 Beerse, Belgium
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ac203165p
Reference19 articles.
1. Incorporation of a nanosplitter interface into an LC-MS-RD system to facilitate drug metabolism studies
2. The use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies
3. HPLC-ICP-MS compared with radiochemical detection for metabolite profiling of3H-bromohexine in rat urine and faeces
4. The potential of inductively coupled plasma mass spectrometry detection for high-performance liquid chromatography combined with accurate mass measurement of organic pharmaceutical compounds
5. Effect of different spray chambers on the determination of organotin compounds by high-performance liquid chromatography–inductively coupled plasma mass spectrometry
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