Preparative Synthesis via Continuous Flow of 4,4,5,5-Tetramethyl-2-(3-trimethylsilyl-2-propynyl)-1,3,2-dioxaborolane: A General Propargylation Reagent-Reference-Cited by-同舟云学术

Preparative Synthesis via Continuous Flow of 4,4,5,5-Tetramethyl-2-(3-trimethylsilyl-2-propynyl)-1,3,2-dioxaborolane: A General Propargylation Reagent

Published:2011-12-16 Issue:5 Volume:16 Page:1131-1140
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Fandrick Daniel R.¹,Roschangar Frank¹,Kim Chunyoung²,Hahm Byoung J.²,Cha Myoung H.²,Kim Hyoun Y.²,Yoo Gyesang²,Kim Taeyun²,Reeves Jonathan T.¹,Song Jinhua J.¹,Tan Zhulin¹,Qu Bo¹,Haddad Nizar¹,Shen Sherry¹,Grinberg Nelu¹,Lee Heewon¹,Yee Nathan¹,Senanayake Chris H.¹

Affiliation:

1. Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc., 900 Ridgebury Road/PO Box 368, Ridgefield, Connecticut, 06877-0368, United States

2. Department of Process R&D Lab, SK Holdings, 140-1 Wonchon-dong, Yuseong-gu, Daejeon 305-712, Korea

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op200180t

Reference35 articles.

1. Boronic Acids

2. Zinc Catalyzed and Mediated Propargylations with Propargyl Boronates